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Table 1 Demographic characteristics and genotype distribution of the patients with rheumatoid arthritis included in the studya

From: CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

Variables Patients (N= 645)
Females 484 (75.0)
Median patient age at time of disease diagnosis, years (IQR) 56 (45 to 65)
Median follow-up, years (IQR) 13 (7 to 19)
Anti-CCP-positive (N = 470) 283 (60.2)
Rheumatoid factor-positive (N = 635) 474 (74.7)
Shared epitope (N = 579) 366 (63.2)
Cardiovascular events 87 (13.5)
   Ischemic heart disease 47 (7.3)
   Cerebrovascular accidents 19 (2.9)
   Heart failure 23 (3.6)
   Peripheral arteriopathy 10 (1.6)
Hypertension (N = 640) 248 (38.8)
Diabetes mellitus (N = 637) 74 (11.6)
Dyslipidemia (N = 621) 282 (45.4)
Obesity (N = 610) 66 (10.8)
Smoking habit (N = 621) 112 (18.0)
CCR5Δ32 rs333  
   CCR5/CCR5 579 (89.8)
   CCR5 /CCR5Δ32 64 (9.9)
   CCR5Δ32 /CCR5Δ32 2 (0.3)
    CCR5 1,222 (94.7)
    CCR5Δ32 68 (5.3)
  1. aAnti-CCP: anticyclic citrullinated peptide antibodies; IQR: interquartile range. Values are n (%) except where indicated otherwise.