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Table 1 Demographic characteristics and genotype distribution of the patients with rheumatoid arthritis included in the studya

From: CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

Variables

Patients (N= 645)

Females

484 (75.0)

Median patient age at time of disease diagnosis, years (IQR)

56 (45 to 65)

Median follow-up, years (IQR)

13 (7 to 19)

Anti-CCP-positive (N = 470)

283 (60.2)

Rheumatoid factor-positive (N = 635)

474 (74.7)

Shared epitope (N = 579)

366 (63.2)

Cardiovascular events

87 (13.5)

   Ischemic heart disease

47 (7.3)

   Cerebrovascular accidents

19 (2.9)

   Heart failure

23 (3.6)

   Peripheral arteriopathy

10 (1.6)

Hypertension (N = 640)

248 (38.8)

Diabetes mellitus (N = 637)

74 (11.6)

Dyslipidemia (N = 621)

282 (45.4)

Obesity (N = 610)

66 (10.8)

Smoking habit (N = 621)

112 (18.0)

CCR5Δ32 rs333

 

   CCR5/CCR5

579 (89.8)

   CCR5 /CCR5Δ32

64 (9.9)

   CCR5Δ32 /CCR5Δ32

2 (0.3)

    CCR5

1,222 (94.7)

    CCR5Δ32

68 (5.3)

  1. aAnti-CCP: anticyclic citrullinated peptide antibodies; IQR: interquartile range. Values are n (%) except where indicated otherwise.