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Table 2 Differences between rheumatoid arthritis patients with or without cardiovascular events according to CCR5Δ32 polymorphisma

From: CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

 

RA patients, n(%)

  

CCR5genotype

With CV events

Without CV events

P value

OR (95% CI)

CCR5/CCR5

84 (96.6)

495 (88.7)

 

1

CCR5/CCR5Δ32

3 (3.4)

61 (10.9)

0.029

0.29 (0.06 to 0.92)

CCR5Δ32/CCR5Δ32

0 (0.0)

2 (0.4)

0.99

0.0 (0.0 to 31.63)

CCR5Δ32 carriers

3 (3.4)

63 (11.3)

0.025

0.28 (0.06 to 0.89)

Allele 2

    

    CCR5

171 (98.3)

1,051 (94.2)

 

1

    CCR5Δ32

3 (1.7)

65 (5.8)

0.024

0.28 (0.06 to 0.88)

  1. aCV: cardiovascular; OR (95% CI): odds ratio with 95% confidence interval; RA: rheumatoid arthritis.