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Table 3 Studies of arterial stiffness in systemic sclerosis

From: Cardiovascular disease in systemic sclerosis - an emerging association?

Reference Total SSc number lSSc number dSSc number Controls number Outcomea Other findings
Andersen et al. [44], 2002 24 20 4 24 AI ↑  
Sfi kakis et al. [39], 2007 24 6 18 52 AI ↔ Four weeks of bosentan therapy had no effect on AI.
Roustit et al. [27], 2008 42 33 9 33 PWV ↔  
Cypiene et al. [37], 2008 17 0 17 34 AI ↑ PWV ↑  
Timar et al. [49], 2008 40 31 9 35 AI ↑ PWV ↑ PWV was higher in patients with limited disease and correlated with disease duration.
Peled et al. [50], 2009 18 - - 13 AI ↔ No difference was found between patients with SSc with and without PAH.
Liu et al. [31], 2011 25 17 8 25 PWV ↑ at forearm and arm PWV ↔ at upper arm, aorta, and leg
  1. aArterial stiffness in patients with systemic sclerosis (SSc) relative to controls: ↑, higher in patients with SSc than controls; ↔, no difference between patients with SSc and controls. AI, augmentation index; dSSc, diffuse systemic sclerosis; lSSc, limited systemic sclerosis; PAH, pulmonary arterial hypertension; PWV, pulse wave velocity.