Table 1 Generalized gait dynamics descriptors for a rat model of lumbar radiculopathy

Mass (g)

285 ± 4

348 ± 6*

325 ± 9*

340 ± 11*

Affected limb

Pre-operative

Sham

NP Alone

NP + sTNFRII

Max F_z (mN)

2,156 ± 65

2,069 ± 79

1,877 ± 88

2,016 ± 85

I_z (mN-s)

416.6 ± 25.5

463.2 ± 31.0

325.4 ± 34.5^∀,#

417.9 ± 33.5

Max F_-x (mN)

-56 ± 15

-170 ± 18*

-111 ± 20

-142 ± 20*

I_-x (mN-s)

-3.5 ± 1.6

-15.3 ± 2.0*

-6.7 ± 2.2

-10.3 ± 2.1

t_-x (% stance time)

20.7 ± 2.8

30.4 ± 3.4

21.2 ± 3.8

27.7 ± 3.7

Max F_x (mN)

177 ± 18

204 ± 22

240 ± 25*

256 ± 24*

I_x (mN-s)

24.0 ± 3.2

28.6 ± 3.9

34.0 ± 4.3

32.9 ± 4.2

Max F_y,0-100% (mN)

280 ± 19

301 ± 23

301 ± 25

286 ± 25

Max F_y,50-100% (mN)

182 ± 12

203 ± 15

185 ± 16

176 ± 16

I_y (mN-sec)

38.9 ± 2.2

46.2 ± 4.3

38.0 ± 4.2

40.4 ± 2.8

Contralateral limb

Pre-operative

Sham

NP Alone

NP + sTNFRII

Max F_z (mN)

2,154 ± 74

2,079 ± 83

1,984 ± 97

1,914 ± 81

I_z (mN-s)

439.5 ± 29.0

475.6 ± 32.6

488.3 ± 38.0

440.3 ± 31.8

Max F_-x (mN)

-79 ± 17

-160 ± 19*

-124 ± 22

-116 ± 19

I_-x (mN-s)

-5.7 ± 1.9

-13.3 ± 2.1*

-11.6 ± 2.4

-6.7 ± 2.0

t_-x (% stance time)

23.4 ± 3.2

30.4 ± 3.6

22.7 ± 4.2

18.1 ± 3.5

Max F_x (mN)

169 ± 21

263 ± 23*

274 ± 27*

304 ± 23*

I_x (mN-s)

23.0 ± 3.6

33.2 ± 4.1

40.2 ± 4.7*

42.4 ± 3.9*

Max F_y,0-100% (mN)

285 ± 21

304 ± 24

276 ± 28

231 ± 23

Max F_y,50-100% (mN)

167 ± 14

210 ± 16

182 ± 18

184 ± 15

I_y (mN-sec)

40.5 ± 2.6

45.2 ± 4.3

49.1 ± 5.7

36.2 ± 3.6