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Table 4 Rates of myocardial infarction and stroke in the all-control population

From: Integrated safety in tocilizumab clinical trials

 

All-control population

n= 4,199

 

Control

n= 1,555

Tocilizumab

4 mg/kg + DMARDs

n= 774

Tocilizumab

8 mg/kg + DMARDs

n= 1,870

Rate/100 PY (95% CI), (number of events)

Myocardial infarction

0.49 (0.13, 1.24), (4)

0.18 (0.00, 0.99), (1)

0.17 (0.02, 0.61), (2)

Stroke

0.24 (0.03, 0.88), (2)

0.0

0.33 (0.09, 0.86), (4)

  1. CI, confidence interval; DMARD, disease-modifying antirheumatic drug; PY, patient-years. Multiple occurrences of the same adverse event in individual patients were counted.
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Arthritis Research & Therapy

ISSN: 1478-6362

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