Effects of DEX on iNOS gene and protein expression and nitrite production. A. iNOS relative gene expression. Values at the y-axis represent the expression level of each gene normalized to that of the no-treatment control (y = 1). Values are mean ± SEM, n = 6 animals. * = P < 0.05 vs. no-treatment control. B. Nitrite released to the medium from days 0 to 4. In each condition, n = 6 cartilage disks. *= P < 0.05 (only comparisons from selected hypotheses are shown). C. Western blot for iNOS protein. DEX, dexamethasone; iNOS, inducible nitric oxide synthase; SEM, standard error of the mean.