Skip to main content

Table 1 Surface integrin levels of the predominant cell types in the rheumatoid arthritis synovium

From: Integrins and their ligands in rheumatoid arthritis

 

α1

α2

α3

α4

α5

α6

αν

β1

β2

β3

β5

Synovial fibroblast

++

-

+(+)

-

+++

+

+++

+++

-

++

?

Macrophage

+

+

+

+++

+++

(+)

+++

+++

++

+++

+

Endothelium

++

+

++

+

+++

+

+++

+++

-

+++

+

T lymphocyte (Th1)

++

+

++

+++

+++

+

+++

+++

++

+++

+

Th17 cell

-

++

++

++

+++

+

+++

+++

++

?

?

B lymphocyte

++

+

++

+++

+++

+

++

+++

++

?

?

  1. For most integrins, expression level data in the literature are given as 'high' or 'strong'. This makes it hard to estimate integrin levels on different cell populations. We consulted several publications and, albeit subjectively, categorized integrin expression levels on a range from strong to weak expression (indicated by one, two, or three plus signs). ?, There is no available data in the literature about the expression of respective integrins.