|
Demographics
|
ACPA+ RA (n= 34)
|
ACPA- RA (n= 25)
|
OA (n= 29)
|
Pvalue
|
|---|
|
Age (years)
|
55 (32 to 80)
|
63 (19 to 80)
|
67 (42 to 83)
| |
|
Gender (females/males)
|
22/12
|
14/11
|
21/8
| |
|
Disease duration (years)
|
7 (0 to 28)
|
8 (0 to 24)
|
Unknown
| |
|
Median IL-17+ cells
|
21 (0 to 118)
|
12 (1 to 61)
|
17 (0 to 50)
|
0.381
|
|
IL-17+ mast cells (%)
|
97 (40 to 100)
|
96 (0 to 100)
|
93 (0 to 100)
|
0.969
|
|
IL-17+ T cells (%)
|
0 (0 to 100)
|
0 (0 to 24)
|
2 (0 to 49)
|
0.558
|
|
IL-17+ MØ (%)
|
0 (0 to 78)
|
4 (0 to 100)
|
1 (0 to 58)
|
0.382
|
|
Median MCs
|
28 (0 to 123)
|
19 (0 to 92)
|
25 (0 to 76)
|
0.198
|
|
MCs (CD117+) expressing IL-17 (%)
|
91 (13 to 100)
|
83 (0 to 100)
|
96 (4 to 100)
|
0.599
|
|
T cells (CD3+), n
|
21 (0 to 592)
|
10 (0 to 115)
|
11 (0 to 265)
|
0.609
|
|
T cells (CD3+) expressing IL-17 (%)
|
0 (0 to 60)
|
0 (0 to 66)
|
1 (0 to 78)
|
0.149
|
|
MØ (CD68+), n
|
71 (1 to 390)
|
53 (1 to 302)
|
66 (2 to 231)
|
0.634
|
|
MØ (CD68+) expressing IL-17 (%)
|
0 (0 to 16)
|
0 (0 to 14)
|
0 (0 to 11)
|
0.689
|
- ACPA: anticitrullinated protein antibody; MC: mast cell; MØ: macrophage; OA: osteoarthritis; RA: rheumatoid arthritis. Results are expressed as medians (minimum-maximum). Mast cells are defined as CD117+ cells, T cells are defined as CD3+ cells and macrophages are defined as CD68+ cells.
