Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls - data from the osteoarthritis initiative

Table 7 Average values of T₂ parameters in the incidence and control groups

Parameter		Compartment ^a	Incidence group (n = 92)	Control group (n = 53)	Pvalue unadjusted	Pvalue adjusted ^b	Coefficient ^c	95% confidence interval
T₂	Mean, ms	All	32.65 ± 1.55	32.07 ± 1.38	0.056	0.018	-0.72	-1.31	-0.12
		MF	37.68 ± 2.28	36.85 ± 2.16	0.042	0.003	-1.18	-1.94	-0.42
		MT	30.27 ± 1.88	29.51 ± 1.77	0.029	0.036	-0.72	-1.39	-0.04
GLCM	Contrast	All	248.67 ± 38.39	227.41 ± 35.00	0.005	0.003	-22.81	-37.48	-8.13
		MF	364.17 ± 68.98	333.37 ± 66.58	0.013	0.009	-32.97	-57.72	-8.21
		MT	257.30 ± 63.19	226.96 ± 47.83	0.004	0.013	-25.40	-45.49	-5.48
	Entropy	All	6.34 ± 0.16	6.30 ± 0.19	0.142	0.286	-0.03	-0.10	0.03
		MF	6.96 ± 0.17	6.90 ± 0.17	0.055	0.062	-0.06	-0.12	0.003
		MT	6.17 ± 0.28	6.09 ± 0.34	0.050	0.127	-0.07	-0.15	0.02
	Variance	All	187.77 ± 26.69	171.74 ± 24.57	0.003	0.002	-16.60	-27.09	-6.27
		MF	255.64 ± 42.38	233.10 ± 38.60	0.003	0.001	-24.86	-39.82	-9.91
		MT	183.65 ± 37.88	162.66 ± 32.01	0.001	0.005	-17.89	-30.31	-5.47

^aAll, average of all compartments: medial femur (MF), medial tibia (MT), lateral femur, lateral tibia, and patella. ^bP value adjusted for age, gender, and body mass index (BMI). ^cThe coefficient is the difference in the T₂ parameter between the incidence and control groups, adjusted for age, gender, and BMI. A coefficient below 0 indicates that the control group has a lower estimated T₂ parameter in comparison with the incidence group. GLCM, grey level co-occurrence matrix.

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