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Table 2 Comparison of the clinical features between RA patients with hRasGRP4 variant 6 and those without

From: Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis

  variant 6 (-) variant 6 (+) P-value
Age (years) 62.6 ± 6.2 61.4 ± 11.2 0.96*
Male/female 0/10 6/7 0.012
DAS28(ESR4) 3.8 ± 1.2 3.4 ± 1.85 0.31*
MMP-3 307 ± 127 148 ± 109 0.057
Disease duration (months)
{mean (range)}
100 (0 to 492) 143 (0 to 504) 0.58*
Patients on therapy 4 8  
Patients on no therapy 2 3 0.77
  1. The P-values in the first four rows (*) were calculated using Mann-Whitney's U-test; the P-values () were calculated by chi-square test with Yates' correction. DAS28, The Disease Activity Score in 28 joints; MMP, matrix metalloproteinase; RA, rheumatoid arthritis