Figure 3

Expression of IL-21R on B- and T-cells of SLE patients. The histograms show a representative example of the expression of IL-21R on CD19⁺-cells (A), CD4⁺-cells (B) and CD8⁺-cells (C). Positive staining (red line) was compared to an isotype control (grey line). The proportion of receptor positive cells is indicated. D shows the IL-21R expression on CD19⁺ B-cells and CD4⁺ and CD8⁺ T-cells from SLE patients (n = 14) in comparison with healthy controls (HC, n = 6). Horizontal lines represent the mean. P-values were calculated using the nonparametric Mann-Whitney U-test.