Table 2 Associations between traditional cardiovascular disease risk factors, IP related factors and insulin resistance after adjustment for age and gender
Variable | Dependent variable †| |
|---|---|---|
|  | HOMA-IR (continuos) ▲ (β-Coefficient (95% CI)) | IR* (HOMA-IR > 2.29) # (Odds ratio (95% CI)) |
Age at time of study (per year) | 0.018 (-0.012, 0.048) | 1.02 (0.99, 1.04) |
Male gender | 0.044 (-0.665, 0.753) | 1.27 (0.67, 2.39) |
Current smoker | 0.004 (-0.747, 0.755) | 0.71 (0.37, 1.37) |
Obese (Y/N) | 1.602 (0.963, 2.240) | 4.02 (1.91, 8.50) |
SBP (per mmHg) | 0.029 (0.007, 0.050) | 1.02 (1.00, 1.04) |
DBP (per mmHg) | 0.043 (0.009, 0.077) | 1.04 (1.01, 1.08) |
TG (per mmol/L) | 1.057 (0.542, 1.572) | 3.95 (2.09, 7.46) |
T.Chol (per mmol/L) | 0.155 (-0.162, 0.472) | 1.19 (0.90, 1.59) |
HDL (per mmol/L) | -1.375 (-2.172, -0.578) | 0.44 (0.21, 0.92) |
LDL (per mmol/L) | 0.193 (-0.169, 0.556) | 1.11 (0.80, 1.53) |
DM (On treatment for DM/DM/fasting glucose ≥ 7.1 mmol/L) | -0.114 (-1.170, 0.942) | 0.73 (0.29, 1.82) |
IP disease duration (per month) | -0.001 (-0.003, 0.001) | 1.00 (1.00, 1.00) |
RF positive | 0.924 (0.254, 1.594) | 2.20 (1.20, 4.06) |
ACPA positive | 1.051 (0.336, 1.767) | 3.00 (1.51, 5.96) |
ACR criteria for RA | 0.542 (-0.114, 1.198) | 1.62 (0.90, 2.93) |
Swollen joint (per joint) | 0.032 (-0.016, 0.080) | 1.03 (0.98, 1.07) |
Tender joint (per joint) | 0.029 (0.002, 0.056) | 1.01 (0.99, 1.04) |
CRP (per mg/L) | 0.007 (-0.012, 0.026) | 1.00 (0.99, 1.02) |
DAS28 | 0.168 (-0.100, 0.437) | 1.05 (0.83, 1.34) |
HAQ | 0.709 (0.237, 1.182) | 1.41 (0.91, 2.19) |
On steroids prior to baseline assessment | -0.300 (-1.094, 0.493) | 0.74 (0.37, 1.48) |
On DMARDs prior to baseline assessment | 0.533 (-0.124, 1.190) | 1.31 (0.73, 2.34) |
On MTX prior to baseline assessment | 0.277 (-0.435, 0.989) | 0.94 (0.50, 1.76) |
On HQC prior to baseline assessment | -0.218 (-1.636, 1.200) | 0.81 (0.24, 2.79) |