Skip to main content

Table 4 Comparison of allele carrier frequencies in RA cases and controls in accordance with the du Montcel classification

From: HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients

Allele

RA patients, n(%) (n= 143)

Controls * , n(%) (n= 1,104)

Χ 2 test

OR (95% CI)

Pvalue

S1

55 (39)

853 (77)

40.3

0.4 (0.3 to 0.5)

<0.0001

S2

28 (20)

110 (10)

10.3

2.0 (1.3 to 3.2)

0.0013

S3D

38 (27)

361 (33)

0.1

0.9 (0.6 to 1.3)

0.7060

S3P

61 (43)

313 (28)

9.6

1.6 (1.2 to 2.2)

0.0019

X

64 (45)

616 (56)

3.6

0.8 (0.6 to 1.0)

0.0571

  1. RA = rheumatoid arthritis. du Montcel classification is from du Montcel et al. [7]. *Data from Robinson and colleagues [31, 32].
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us