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Table 1 Clinical characteristics of the study populations

From: Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease

Clinical and biological features SSc (n: 33) HD (n: 29) P
Women, n (%) 29 (87.9) 23 (79.3) ns
Age, median (range) 52 (30 to 80) 50 (18 to 68) ns
Ethnicity: Caucasian (%) 30 (90) 29 (100) ns
Diffuse cutaneous SSc, n (%) 20 (60.6) N/A  
Age onset, mean (+/- SD) 44 (14) N/A  
Disease duration, median (range) 7 (1 to 32) N/A  
ANA positivity (%) 29 (87.9) N/A  
ACA positivity (%) 4 (12.1) N/A  
Anti-Scl70 positivity (%) 11 (33.3) N/A  
Digital ulcers 19 (57.6) N/A  
Calcinosis 9 (27.3) N/A  
Arthritis 7 (21.2) N/A  
PAH, n (%) 4 (12.1) N/A  
ILD, n (%) 14 (42.4) N/A  
Current immunosuppressive therapy (%) 0 N/A  
  1. ANA, anti-nuclear antibodies; ACA, anti-centromere antibodies; ILD, interstitial lung disease; PAH, pulmonary artery hypertension; N/A: not applicable. P as determined by the Fisher's exact test. ILD was observed on HRCT and confirmed by a TLC < 80% of the predicted value. Pre-capillary PAH was defined as a mean resting pulmonary artery pressure > 25 mmHg in presence of a pulmonary capillary wedge pressure £15 mmHg by a right heart catheterization.