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Table 3 Expression of transcription factors in peripheral monocytes

From: Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome

Transcription factor Normal pSS
NF-IL6 100.0 ± 16.0 623.6 ± 85.8***
NF-IL6β 100.0 ± 18.5 252.8 ± 51.5*
NF-κB1 100.0 ± 11.4 167.5 ± 23.4*
NF-κB2 100.0 ± 14.9 342.6 ± 45.4***
  1. pSS = primary Sjögren's syndrome. Total RNAs were extracted from monocytes prepared as described in the Table 2 footnote, and the expression levels of NF-IL6, NF-IL6β, NF-κB1 and NF-κB2 were quantitated. The relative expression levels of the genes are indicated. Data represent means ± SEM. Asterisk denotes statistically significant difference between "Normal" and "pSS." *P < 0.05 and ***P < 0.001.