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Table 1 Baseline patient characteristics by vaccination status

From: The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study

 

Vaccination status

Baseline characteristics, n(%)

Vaccinated

n= 551

Unvaccinated

n= 43,564

Age groups (years)

  

   50 to 59

202 (36.7)

30,156 (69.2)

   60 to 64

275 (49.9)

9,573 (22.0)

   65 and older

74 (13.4)

3,835 (8.8)

Women

352 (63.9)

27,091 (62.2)

Inflammatory/Autoimmune disease

  

   RA

206 (37.4)

19,120 (43.9)

   Psoriatic arthritis

11 (2.0)

856 (2.0)

   Psoriasis

146 (26.5)

10,566 (24.3)

   Inflammatory bowel diseases

136 (24.7)

8,503 (19.5)

   Ankylosing spondylitis

8 (1.5)

625 (1.4)

   Multiple diseases

44 (8.0)

3,894 (8.9)

Medicationsa

  

   TNF antagonists user

27 (4.9)

4,186 (9.6)

   Other biologics user

0 (0)

198 (0.5)

   Conventional DMARDs user

92 (16.7)

9,312 (21.4)

   Oral glucocorticoidsb

  

None

456 (82.8)

34,267 (78.7)

Low

86 (15.6)

8,041 (18.5)

Medium

7 (1.3)

902 (2.1)

High

2 (0.4)

354 (0.8)

Charlson comorbidity index

  

   0

287 (52.1)

19,971 (45.8)

   1

181 (32.9)

16,565 (38.0)

   ≥ 2

83 (15.1)

7,028 (16.1)

Inpatient hospitalization

  

   No

466 (84.6)

36,158 (83.0)

   Yes

45 (15.4)

7,406 (17.0)

Number of outpatient physician visits

  

   0-2

83 (15.1)

8,705 (20.0)

   3-5

227 (41.2)

16,843 (38.7)

   6-10

185 (33.6)

13,376 (30.7)

   11 and more

54 (9.8)

4,642 (10.7)

  1. DMARDS, Disease-modifying antirheumatic drugs; RA, rheumatoid arthritis; TNF, tumor necrosis factor. aMeasured in the 6-month baseline period before the start of observation
  2. bCumulative average daily prednisone-equivalent glucocorticoid dose in the past 183 days: none, low (< 10 mg/day), medium (10-20 mg/day), and high (> 20 mg/day).