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Table 1 Lacrimal gland gene expression reduced by treatment of mice with LTBR-Ig compared to control.

From: Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome

 

Gene

Fold Change Down

Glycam1

glycosylation dependent cell adhesion molecule 1

29.02

Serpina1b

serine (or cysteine) preptidase inhibitor, clade A, member 1b

12.30

Sell

selectin, lymphocyte

11.43

Pla2g2d

phospholipase A2, group IID

10.53

Igh-1a

IgG2a heavy chain

8.47

Faim3

Fas apoptotic inhibitory molecule 3

8.09

Ccl19

CCL19 chemokine

7.67

Cxcr5

C-X-C Chemokine receptor type 5

7.59

Rnase6

ribonuclease, RNase A family, 6

7.19

Clca2

chloride channel calcium activated 2

6.77

Cxcr4

chemokine (C-X-C motif) receptor 4

6.71

Aff3

AF4/FMR2 family, member 3

6.46

Ebf1

early B-cell factor 1

6.42

Rasal3

RAS protein activator like 3

6.34

Hhex

hematopoietically expressed homeobox

6.23

Fcrl1

Fc receptor-like 1

6.18

Fcer2a

Fc receptor, IgE, low affinity II, alpha polypeptide

6.17

Btk

Bruton agammaglobulinemia tyrosine kinase

6.12

Cd37

CD37 antigen

6.09

Btla

B and T lymphocyte associated

6.07

B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

5.67

Cxcl13

chemokine (C-X-C motif) ligand 13

5.57

Fcrl1

Fc receptor-like 1

5.57

Ubd

ubiquitin D

5.54

Fam55c

family with sequence similarity 55, member C

5.53

Cr2

complement receptor 2

5.49

Fcer2a

Fc receptor, IgE, low affinity II, alpha polypeptide

5.39

H2-Ob

histocompatibility 2, O region beta locus

5.38

Bank1

B-cell scaffold protein with ankyrin repeats 1

5.36

Stat4

signal transducer and activator of transcription 4

5.26

Ptprc

protein tyrosine phosphatase, receptor type, C

5.25

Cd38

CD38 antigen

5.19

Ms4a1

membrane-spanning 4-domains, subfamily A, member 1

5.19

Pde7a

phosphodiesterase 7A

5.16

Lrrk2

leucine-rich repeat kinase 2

5.15

Plekha2

pleckstrin homology domain-containing, family A

5.14

Slamf6

SLAM family member 6

5.07

Slc2a3

solute carrier family 2 (facilitated glucose transporter), member 3

5.04

Tcrb-V13

T-cell receptor beta, variable 13

5.00