Figure 3From: Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways Ex vivo cartilage releases adiponectin and its concentration correlates with NO, IL-6 and MMP-3 production. Scatterplots show positive correlations between adiponectin and NO (A), IL-6 (B) and matrix metalloproteinase 3 (MMP-3) (C) released by osteoarthritis (OA) cartilage into the culture medium. Cartilage samples were collected from 35 OA patients undergoing knee replacement surgery.Back to article page