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Table 1 Demographic features and symptom scores in fibromyalgia patients and controls.

From: Nocturnal heart rate variability parameters as potential fibromyalgia biomarker: correlation with symptoms severity

Variable

Fibromyalgia

(n = 22)

Control

(n = 22)

P value

Age (years)

32.4 ± 7.9

30.4 ± 7.4

0.406

Body mass index (kg/m2)

24.6 ± 4.4

25.0 ± 3.2

0.719

Disease duration (years)

6.8 ± 6.1

N/A

N/A

Total FIQ score

64.8 ± 14.1

12.0 ± 10.7

< 0.0001

   VAS disability

6.5 ± 2.3

0.5 ± 1.1

< 0.0001

   VAS pain

7.2 ± 2.2

0.7 ± 1.5

< 0.0001

   VAS fatigue

8.3 ± 1.4

1.8 ± 2.2

< 0.0001

   VAS sleep

7.3 ± 3.1

2.1 ± 2.4

< 0.0001

   VAS morning stiffness

7.2 ± 2.5

0.7 ± 1.4

< 0.0001

   VAS anxiety

7.3 ± 2.4

2.1 ± 2.3

< 0.0001

   VAS depression

6.3 ± 3.1

1.8 ± 2.5

< 0.0001

Total COMPASS score

53.6 ± 18.2

13.5 ± 10.6

< 0.0001

   Orthostatic intolerance

20.4 ± 9.6

5.2 ± 5.8

< 0.0001

   Vasomotor domain

3.3 ± 2.9

0.4 ± 1.1

< 0.0001

   Secretomotor

4.7 ± 3.6

1.0 ± 1.5

< 0.0001

   Gastroparesis

2.9 ± 1.5

0.5 ± 0.7

< 0.0001

   Diarrhea

7.4 ± 5.4

2.5 ± 3.1

0.001

   Constipation

4.4 ± 2.4

1.1 ± 1.2

< 0.0001

   Bladder

4.0 ± 4.7

1.0 ± 1.6

0.010

   Pupillomotor

2.8 ± 1.2

0.7 ± 1.1

< 0.0001

   Sleep

2.8 ± 1.7

0.5 ± 0.8

< 0.0001

   Syncope

0.5 ± 1.4

0.1 ± 0.8

0.305

   Understatement index

0.8 ± 1.3

3.0 ± 2.9

0.003

   Psychosomatic index

1.2 ± 1.5

0.2 ± 0.6

0.004

MAF

40.3 ± 5.5

15.6 ± 11.3

< 0.0001

MOS

60.5 ± 11.2

19.2 ± 10.4

< 0.0001

SF-36 mental component

38.9 ± 5.3

42.2 ± 5.2

0.043

SF-36 physical component

53.0 ± 7.6

63.0 ± 83

< 0.0001

HADS depression

7.3 ± 3.0

3.9 ± 4.4

0.005

HADS anxiety

12.3 ± 4.0

5.5 ± 2.9

< 0.0001

  1. COMPASS, composite autonomic symptom scale; FIQ, fibromyalgia impact questionnaire; HADS, hospital anxiety and depression scale; MAF, multidimensional assessment of fatigue; MOS, medical outcome sleep scale; SF-36, short form 36 items health survey; VAS, visual analogue scale. N/A = not applicable.