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Table 1 Demographic features and symptom scores in fibromyalgia patients and controls.

From: Nocturnal heart rate variability parameters as potential fibromyalgia biomarker: correlation with symptoms severity

Variable Fibromyalgia (n = 22) Control (n = 22) P value
Age (years) 32.4 ± 7.9 30.4 ± 7.4 0.406
Body mass index (kg/m2) 24.6 ± 4.4 25.0 ± 3.2 0.719
Disease duration (years) 6.8 ± 6.1 N/A N/A
Total FIQ score 64.8 ± 14.1 12.0 ± 10.7 < 0.0001
   VAS disability 6.5 ± 2.3 0.5 ± 1.1 < 0.0001
   VAS pain 7.2 ± 2.2 0.7 ± 1.5 < 0.0001
   VAS fatigue 8.3 ± 1.4 1.8 ± 2.2 < 0.0001
   VAS sleep 7.3 ± 3.1 2.1 ± 2.4 < 0.0001
   VAS morning stiffness 7.2 ± 2.5 0.7 ± 1.4 < 0.0001
   VAS anxiety 7.3 ± 2.4 2.1 ± 2.3 < 0.0001
   VAS depression 6.3 ± 3.1 1.8 ± 2.5 < 0.0001
Total COMPASS score 53.6 ± 18.2 13.5 ± 10.6 < 0.0001
   Orthostatic intolerance 20.4 ± 9.6 5.2 ± 5.8 < 0.0001
   Vasomotor domain 3.3 ± 2.9 0.4 ± 1.1 < 0.0001
   Secretomotor 4.7 ± 3.6 1.0 ± 1.5 < 0.0001
   Gastroparesis 2.9 ± 1.5 0.5 ± 0.7 < 0.0001
   Diarrhea 7.4 ± 5.4 2.5 ± 3.1 0.001
   Constipation 4.4 ± 2.4 1.1 ± 1.2 < 0.0001
   Bladder 4.0 ± 4.7 1.0 ± 1.6 0.010
   Pupillomotor 2.8 ± 1.2 0.7 ± 1.1 < 0.0001
   Sleep 2.8 ± 1.7 0.5 ± 0.8 < 0.0001
   Syncope 0.5 ± 1.4 0.1 ± 0.8 0.305
   Understatement index 0.8 ± 1.3 3.0 ± 2.9 0.003
   Psychosomatic index 1.2 ± 1.5 0.2 ± 0.6 0.004
MAF 40.3 ± 5.5 15.6 ± 11.3 < 0.0001
MOS 60.5 ± 11.2 19.2 ± 10.4 < 0.0001
SF-36 mental component 38.9 ± 5.3 42.2 ± 5.2 0.043
SF-36 physical component 53.0 ± 7.6 63.0 ± 83 < 0.0001
HADS depression 7.3 ± 3.0 3.9 ± 4.4 0.005
HADS anxiety 12.3 ± 4.0 5.5 ± 2.9 < 0.0001
  1. COMPASS, composite autonomic symptom scale; FIQ, fibromyalgia impact questionnaire; HADS, hospital anxiety and depression scale; MAF, multidimensional assessment of fatigue; MOS, medical outcome sleep scale; SF-36, short form 36 items health survey; VAS, visual analogue scale. N/A = not applicable.