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Table 4 Predictive value of heart rate variability indexes in 22 patients with fibromyalgia and 22 controls.

From: Nocturnal heart rate variability parameters as potential fibromyalgia biomarker: correlation with symptoms severity

  Sensitivity (%) Specificity (%) PPV (%) NPV (%)
24-hour     
Mean NN ≤ 779 ms 73 55 62 67
SDNN ≤ 141 ms 68 68 68 68
SDANN ≤ 119 ms 64 68 67 65
SDSD ≤ 40 ms 64 68 67 65
RMSSD ≤ 40 ms 64 68 67 65
pNN50 ≤ 13% 55 73 67 62
Sleeping hours     
Mean NN ≤ 922 ms 73 59 64 68
SDNN ≤ 114 ms 86 68 73 83
SDANN ≤ 59 ms 68 82 79 72
SDSD ≤ 44 ms 55 73 67 62
RMSSD ≤ 44 ms 55 73 67 62
pNN50 ≤ 31% 68 55 60 63
  1. Mean NN, mean NN interval; pNN50, percentage of adjacent pairs of R-R intervals that differ by more than 50 ms from each other in a given time period; ms, milliseconds; RMSSD, square root of the mean of the squares of differences between adjacent NN intervals; SDANN, mean standard deviation of the average NN intervals calculated over 5 minutes; SDNN, standard deviation of the NN intervals; SDSD, standard deviation of the successive NN differences.