Table 1 Primary, secondary SS and non-SS sicca patients' demographic and clinical features
Data | pSS (40) | Sicca non-SS (10) | RA-sSS (8) | SSc-sSS (7) |
|---|---|---|---|---|
Sex | 40 F:0M | 10 F:0M | 8 F:0 M | 7F:0M |
Age (yrs) | 52.4 ± 10.5 | 56.0 ± 10.7 | 60.8 ± 11.4 | 61.7 ± 8.1 |
Disease duration (yrs) | 7 ± 6 | 3 ± 2 | 9 ± 7 | 7 ± 4 |
Oral symptoms | 98% | 80% | 100% | 86% |
Ocular symptoms | 97% | 80% | 100% | 100% |
Ocular tests (1) | 100% | 70% | 100% | 100% |
Difficult in swallowing | 19% | 2% | 12% | 71% |
Salivary gland enlargement | 32% | none | 12% | none |
Minor salivary gland biopsy grading: | ||||
Chisolm and Mason grade 0, 1, 2 | None | 10/10 | 5/8 | 1/7 |
Chisolm and Mason grade 3 | 20/40 | none | 3/8 | 5/7 |
Chisolm and Mason grade 4 | 20/40 | none | none | 1/7 |
Arthralgia | 76% | 1% | 100% | 57% |
Arthritis | 6% | none | 100% | none |
Fatigue | 73% | 30% | 25% | 29% |
Raynaud's phenomenon | 43% | 2% | 12% | 100% |
Skin involvement | 16% | none | 37% | 14% |
Dyspareunia | 32% | 2% | none | 14% |
Interstitial lung disease | None | none | 12% | 14% |
Peripheral nervous involvement | 3% | none | 12% | none |
Kidney involvement | 3% | none | none | none |
Leucopenia | 30% | none | 12% | 14% |
Low C3 and/or C4 levels | 33% | 1% | 12% | 14% |
Hypergammaglobulinemia | 62% | none | 37% | none |
Antinuclear antibodies | 94% | 90% | 62% | 100% |
Anti-Ro/SSA | 70%/ | none | 25% | 14% |
Anti-La/SSB | 36% | none | 12% | none |
Rheumatoid Factor | 80% | 2% | 100% | 29% |