Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes

Table 2 MS/MS data of differential protein spots from pSS, non-SS sicca syndrome and sSS syndromes

Spot No	Accession No ^a	Protein name	Gene name	Theoretical Mr ^b	Theoretical pI ^b	Matched peptides ^c	Coverage (%)	Peptides identified ^d
2261	P04745	α-amylase 1	AMY1A	58	6.47	16	43	RSGNEDEFRN
2842	Q6GMW1	IGKC protein	IGKC	26	6.9	8	33	KSFNRGE
2439 2543	P06733	α-enolase	ENO1	47	7.01	8	25	RNFRNPLAK
2640 2642	P04406	G3PDH	GAPDH	36	8.57	3	9	KAGAHLQGGAKRV
3017 3034	P06702	Protein S100-A9	S100A9	13	5.71	4	43	RLTWASHEKM
2996	P01034	Cystatin-C	CST3	16	9.00	6	49	KASNDMYHSRA
3018	P31151	Protein S100-A7	S100A7	11	6.27	3	26	RSIIGMIDMFHKY
2832	A0N5G5	Rheumatoid factor D5 light chain (Fragment)	V<kappa>3	13	9.15	2	23	RLLIYDASNRA
2954	P31025	Lipocalin-1	LCN1	19	5.39	3	27	RGLSTESILIPRQ

a) Accession number was derived from the ExPASy database. b) Theoretical molecular weight (kDa) and pI from the ExPASy database. c) The number of peaks which match to the trypsin peptides. d) Each spot corresponding to one certain protein had at least one of the shown peptides identified.
G3PDH, glyceraldehydes-3-phosphate dehydrogenase; IGKC: immunoglobulin k light chain; pSS, primary Sjögren's syndrome; SS: Sjögren's syndrome; SSc-sSS secondary Sjögren's syndrome concomitant to systemic sclerosis; sSS: secondary Sjögren's syndrome.

ISSN: 1478-6362