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Table 5 Mean values of salivary marker proteins

From: Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes

 

β-2 microglobulin

mean ± SD (μg/ml)

α-enolase

mean ± SD (ng/ml)

α-amylase

mean ± SD (U/mg of proteins)

pSS

1.7 ± 0.5

82.4 ± 34.1

35.7 ± 17.5

healthy

0.8 ± 0.3

37.0 ± 27.3

34.5 ± 15.5

P-value vs pSS

<0.001

0.002

0.893

sicca non-SS

1.3 ± 0.7

74.2 ± 33.4

40.0 ± 18.7

P-value vs pSS

0.08

0.191

0.538

RA- sSS

1.5 ± 0.8

103.0 ± 15.4

35.3 ± 19.9

P-value vs pSS

0.514

0.204

0.96

SSc-sSS

1.5 ± 0.6

78.2 ± 31.6

38.0 ± 22.3

P-value vs pSS

0.05

0.392

0.718

  1. pSS, primary Sjögren's syndrome; RA-sSS, secondary Sjögren's syndrome concomitant to rheumatoid arthritis; SSc, systemic sclerosis; SSc-sSS, secondary Sjögren's syndrome (sSS) concomitant to systemic sclerosis; sSS, secondary Sjögren's syndrome.