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Table 5 Mean values of salivary marker proteins

From: Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes

  β-2 microglobulin
mean ± SD (μg/ml)
α-enolase
mean ± SD (ng/ml)
α-amylase
mean ± SD (U/mg of proteins)
pSS 1.7 ± 0.5 82.4 ± 34.1 35.7 ± 17.5
healthy 0.8 ± 0.3 37.0 ± 27.3 34.5 ± 15.5
P-value vs pSS <0.001 0.002 0.893
sicca non-SS 1.3 ± 0.7 74.2 ± 33.4 40.0 ± 18.7
P-value vs pSS 0.08 0.191 0.538
RA- sSS 1.5 ± 0.8 103.0 ± 15.4 35.3 ± 19.9
P-value vs pSS 0.514 0.204 0.96
SSc-sSS 1.5 ± 0.6 78.2 ± 31.6 38.0 ± 22.3
P-value vs pSS 0.05 0.392 0.718
  1. pSS, primary Sjögren's syndrome; RA-sSS, secondary Sjögren's syndrome concomitant to rheumatoid arthritis; SSc, systemic sclerosis; SSc-sSS, secondary Sjögren's syndrome (sSS) concomitant to systemic sclerosis; sSS, secondary Sjögren's syndrome.