TY - JOUR AU - Mooney, Robert A. AU - Sampson, Erik R. AU - Lerea, Jaclyn AU - Rosier, Randy N. AU - Zuscik, Michael J. PY - 2011 DA - 2011/12/07 TI - High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury JO - Arthritis Research & Therapy SP - R198 VL - 13 IS - 6 AB - Increasing obesity and type 2 diabetes, in part due to the high-fat (HF) Western diet, parallels an increased incidence of osteoarthritis (OA). This study was undertaken to establish a causal relation between the HF diet and accelerated OA progression in a mouse model and to determine the relative roles of weight gain and metabolic dysregulation in this progression. SN - 1478-6354 UR - https://doi.org/10.1186/ar3529 DO - 10.1186/ar3529 ID - Mooney2011 ER -