TY - JOUR AU - de Groot, Lodewijk AU - Hinkema, Helmy AU - Westra, Johanna AU - Smit, Andries J. AU - Kallenberg, Cees GM AU - Bijl, Marc AU - Posthumus, Marcel D. PY - 2011 DA - 2011/12/14 TI - Advanced glycation endproducts are increased in rheumatoid arthritis patients with controlled disease JO - Arthritis Research & Therapy SP - R205 VL - 13 IS - 6 AB - Advanced glycation end products (AGEs) are produced and can accumulate during chronic inflammation, as might be present in patients with rheumatoid arthritis (RA). AGEs are involved in the development of cardiovascular disease. The aim of this study is to evaluate whether AGEs are increased in patients with long-standing RA and whether AGE accumulation is related to disease activity, disease severity and measures of (premature) atherosclerosis, such as endothelial activation, endothelial dysfunction and intima media thickness (IMT). SN - 1478-6354 UR - https://doi.org/10.1186/ar3538 DO - 10.1186/ar3538 ID - de Groot2011 ER -