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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Mutations in genes encoding complement inhibitors CD46 and CFHaffect the age at nephritis onset in patients with systemic lupus erythematosus

Figure 1

Age at onset of nephritis in systemic lupus erythematosus patients. Median (range) age of nephritis diagnosis for systemic lupus erythematosus patients with or without FH/CD46 mutations, respectively: (A) Southern Sweden cohort, 28 (15 to 42) years and 33 (10 to 68) years; (B) mid Sweden cohort, 22 (12 to 51) years and 32 (9 to 84) years; and (C) combined cohort, 24 (12 to 51) years and 32 (9 to 84) years. Horizontal line, median for each dataset. Statistical significances of differences between patients carrying mutations and those without CD46 and CFH were evaluated by nonparametric Mann-Whitney test with a two-tailed P value.

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Arthritis Research & Therapy

ISSN: 1478-6362

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