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Table 1 Characteristics of patients and satellite cell isolation

From: Regenerative potential of human muscle stem cells in chronic inflammation

  Total study population Selected study population
  RA
N= 11
OA
N= 16
RA
N= 4
OA
N= 8
Age (years) 64 (12) 64 (9) 65 (9) 64 (9)
Gender (% female) 91 56 75 50
Disease duration (years) 16 (13) - 15 (13) -
CRP (mg/L) 12 (11) 2 (3) 10 (7) 2 (3)
ESR (mm) 28 (13) 11 (6) 28 (15) 11 (7)
Leucocytes (*109/L) 10.5 (2.5) 7.0 (1.6) 9.7 (1.4) 7.2 (1.6)
Myogenic purity after explantation (% desmin positive cells) 34 (20) 46 (26) 46 (13) 58 (26)
Spontaneous differentiation* (%) 18 19 0 0
Sufficient biopsy quality# (%) 36 50 100 100
  1. CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; N, number of subjects; OA, osteoarthritis; RA, rheumatoid arthritis. Values are given as mean (SD) if not otherwise stated.
  2. CRP and leukocyte data were available for 14 and 10 patients in the OA and RA group respectively. ESR data were available for 7 patients in OA group and 10 patients in the RA group. *Spontaneous differentiation was defined as 10 or more myotubes with more than 2 nuclei in a 100 mm culture dish. #Sufficient biopsy quality was defined as no spontaneous differentiation and myogenic purity higher than 75% after CD56 cell selection.