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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

Figure 3

Plots of morphometric parameters of subchondral trabecular bone determined by micro-CT in the control tibiae and in the MIA-injected tibiae, at two, six, and ten weeks post-MIA injection. There was a statistically significant increase over time in BV, BV/TV, Tb.Th, and Tb.N, and a decrease in Tb.Sp, in both the control and MIA-injected tibiae. Error bars = SD. BV, bone volume; BV/TV, bone volume fraction; CT, computed tomography; MIA, monosodium iodoacetate; TB.N, trabecular number; Tb.Sp, trabecular separation; Tb.Th, trabecular thickness. * P < 0.05, ** P < 0.01, *** P < 0.001, between control tibiae and MIA-injected tibiae.

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