TY - JOUR AU - Yukawa, Naoichiro AU - Fujii, Takao AU - Kondo-Ishikawa, Seiko AU - Yoshifuji, Hajime AU - Kawabata, Daisuke AU - Nojima, Takaki AU - Ohmura, Koichiro AU - Usui, Takashi AU - Mimori, Tsuneyo PY - 2011 DA - 2011/12/22 TI - Correlation of antinuclear antibody and anti-double-stranded DNA antibody with clinical response to infliximab in patients with rheumatoid arthritis: a retrospective clinical study JO - Arthritis Research & Therapy SP - R213 VL - 13 IS - 6 AB - The induction of antinuclear antibodies (ANAs) or anti-double-stranded (ds) -DNA antibodies (Abs) after infliximab (IFX) therapy in rheumatoid arthritis (RA) is a well-known phenomenon, but the correlation of such Abs with the clinical response to IFX has not yet been determined. The aims of this retrospective observational study were to examine the prevalence of positive ANA and anti-ds-DNA Abs before and after IFX therapy in patients with RA and to investigate whether an increased titer of such Abs is associated with the clinical efficacy of IFX. SN - 1478-6354 UR - https://doi.org/10.1186/ar3546 DO - 10.1186/ar3546 ID - Yukawa2011 ER -