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Table 4 The association between baseline dietary factors and lipids with incident BMLsa

From: A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee

 

Univariate

Multivariableb

 

OR (95% CI)

P

OR (95% CI)

P

Dietary factors

    

   Energy intake

0.68 (0.34, 1.37)

0.282

0.64 (0.29, 1.39)

0.257

   Total fat

0.40 (0.17, 0.93)

0.034

0.32 (0.12, 0.86)

0.023

   Carbohydrate

0.96 (0.53, 1.71)

0.877

0.95 (0.51, 1.75)

0.857

   Protein

0.79 (0.38, 1.67)

0.542

0.78 (0.35, 1.75)

0.552

   Sugars

0.98 (0.54, 1.75)

0.933

0.96 (0.52, 1.73)

0.856

Individual fats

    

   Monounsaturated fat

0.49 (0.22, 1.09)

0.080

0.41 (0.16, 1.04)

0.061

   Polyunsaturated fat

0.82 (0.44, 1.52)

0.523

0.82 (0.42, 1.57)

0.540

   Saturated fat

0.29 (0.11, 0.78)

0.014

0.24 (0.08, 0.72)

0.010

Lipids

    

   Total cholesterol

0.81 (0.44, 1.46)

0.479

0.67 (0.33, 1.35)

0.262c

   Triglycerides

0.69 (0.33, 1.45)

0.329

0.75 (0.34, 1.65)

0.474c

   LDL cholesterol

1.18 (0.67, 2.07)

0.570

1.05 (0.55, 1.98)

0.886c

   HDL cholesterol

0.52 (0.27, 1.03)

0.060

0.34 (0.14, 0.78)

0.011 c

  1. aNo BML present at baseline and follow-up (n = 212) versus incident BML (n = 14) at any site (medial tibial, medial femoral, lateral tibial, and lateral femoral). Odds ratios (ORs) have been standardized. bAdjusted for age, sex, body mass index, and radiographic osteoarthritis. cFurther adjusted for statin use. Boldface denotes a statistically significant result. BML, bone marrow lesion; 95% CI, 95% confidence interval; HDL, high-density lipoprotein; LDL, low-density lipoprotein; P, P value.
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Arthritis Research & Therapy

ISSN: 1478-6362

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