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Table 7 Genes linked to the cell cycle that are significantly down-regulated

From: Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice

Symbol Name Function
Cyclins and cyclin kinases
Ccna2 Cyclin a2  
Ccnb1 Cyclin b1  
Ccnb2 Cyclin b2  
Ccnd3 Cyclin d3  
Ccne1 Cyclin e1  
Ccne2 Cyclin e2  
Cdk1 Cyclin dependent kinase 1  
Cdk2 Cyclin dependent kinase 2  
Checkpoint regulators
Bub1 budding uninhibited by benzimidazoles 1 Kinase in spindle checkpoint function
Bub1b budding uninhibited by benzimidazoles 1b Kinase in spindle checkpoint function
Chek1 CHK1 checkpoint homolog Checkpoint regulator of cell cycle
Chek2 CHK2 checkpoint homolog Checkpoint regulator of cell cycle
Mad2l1 mitotic arrest deficient, homolog-like 1 Mitotic spindle checkpoint
Minichromosome complex
Mcm2 minichromosome maintenance deficient 2 mitotin Regulator of cell cycle
Mcm4 minichromosome maintenance deficient 4 Regulator of cell cycle
Mcm5 minichromosome maintenance deficient 5 Regulator of cell cycle
Mcm6 minichromosome maintenance deficient 6 Regulator of cell cycle
Mcm7 minichromosome maintenance deficient 7 Regulator of cell cycle
Transcription factors
E2F2 E2F transcription factor 2 Regulator of cell cycle
Tpdp1 Transcription factor DP1 Partner of E2F transcription factors
Tfdp2 Transcription factor DP1 Partner of E2F transcription factors
Ttk Ttk protein kinase Mitosis associated kinase
Other cell cycle regulators
Cdc6 cell division cycle 6 homolog Regulator of cell cycle
Cdc20 cell division cycle 20 homolog Regulator of cell cycle
Cdc25a cell division cycle 25a homolog Regulator of cell cycle
Cdc25b cell division cycle 25b homolog Regulator of cell cycle
Cdc45 cell division cycle 45 homolog Regulator of cell cycle
Dbf4 DBF4 homolog (S. cerevisiae) Activator of S-phase kinase
Espl1 extra spindle poles-like 1 Cleavage of sister chromatids
Fzr1 fizzy/cell division cycle 20 related 1 Activation of the anaphase promoting complex during mitosis
GADD45A Growth arrest and DNA damage inducible gene 45a Regulator of DNA repair and inhibitor of the S phase
Orc1 origin recognition complex, subunit 1 Initiation of DNA replication
Orc6 origin recognition complex, subunit 6 Initiation of DNA replication
Plk1 Polo-like kinase 1 Promoter of mitosis
Pcna proliferating cell nuclear antigen Cofactor of DNA polymerase delta
Rb1 Retinoblastoma 1 Regulator of the cell cycle
Rbl1 Retinoblastoma like 1 Regulator of the cell cycle