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Table 2 Measures of pulmonary function in AS patients and controls

From: Restrictive pulmonary function is more prevalent in patients with ankylosing spondylitis than in matched population controls and is associated with impaired spinal mobility: a comparative study

PFT AS patients (n= 147) Controls (n= 121) ß (95% CI) P-value
FVC (liters) mean (SD) 4.0 (1.2) 4.1 (1.0) 0.3 (0.14,0.45) < 0.001a
FVC% 97.2 (18.1) 104.9 (15.2)   < 0.001b
FEV1 (liters) mean (SD) 3.1 (0.9) 3.2 (0.9) 0.3 (0.18,0.43) < 0.001a
FEV1% 89.8 (16.0) 98.5 (14.5)   < 0.001b
PEF (liters/minute) mean (SD 464.7 (121.4) 469.1 (120.1) 20.5 (1,41.1) 0.05a
PEF% 95.2 (17.6) 99.4 (16.6)   0.05b
FEV1/FVC% 76.5 (7.5) 77 (6.4)   0.38b
Respiratory pattern     
Normal n (%) 105 (71.4) 110 (90.9)   < 0.001c
Restrictive pattern n (%) 27 (18.4) 0   < 0.001c
Obstructive pattern n (%) 15 (10.2) 11 (9.1)   0.76c
  1. FVC, forced vital capacity; FEV1, forced expiratory volume in one second; PEF, peak expiratory flow; FVC%, FEV1%, PEF%, predicted percentages adjusted for age, gender, smoking and height (adjustments made in the device); FEV1/FVC%, absolute ratio (derived from observed values). A, linear regression, adjusted for age, gender, smoking and height; b, t-test; c, chi-square test