A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis

Table 1 Characteristics of 58 patients with rheumatoid arthritis

Variable	Statistic
Age, years	54.0 (47.9, 63.0)
Sex, female	34 (59%)
RA disease durations, months^†	18.8 (11.3, 35.9)
Pain (0 to 100 mm)	30 (16, 69)
Patient global assessment (0 to 100 mm)	28.5 (12, 63)
Morning stiffness duration, minutes	30 (15, 90)
HAQ disability index (0 to 3)	0.5 (0.1, 1.4)
RF positive^‡	53 (93%)
ACPA positive^§	44 (80%)
C-reactive protein, mg/L	5.9 (3.0, 11.1)
CMV IgG positive	28 (48%)
EBV IgG positive	55 (95%)
DAS28	4.4 (3.4, 5.4)
Radiographic damage scores (SHS), units
Total	18.5 (8, 37)
Erosions	11.5 (3, 30)
Joint space narrowing	4.5 (3, 12)
Medications
Methotrexate	49 (86%)
Biologic response modifiers	14 (24%)
Corticosteroids	27 (47%)

*Values are median (interquartile range) for continuous variables or number (%) for categorical variables. ^†The duration of disease from onset of arthritis symptoms. ^‡Of 57 patients tested. ^§Of 55 patients tested. ACPA, anti-citrullinated protein antibodies; CMV, cytomegalovirus; DAS28, Disease Activity Score in 28 joints, 4-variable version, using the C-reactive protein; EBV, Epstein-Barr virus; HAQ, Health Assessment Questionnaire; IgG, immunoglobulin G; RA, rheumatoid arthritis; RF, rheumatoid factor; SHS, Sharp-van der Heijde score

ISSN: 1478-6362