Time post-ACLX | CT diameter (mm) | MRI diameter (mm) | vBMD (mg/cc) | OARSI grade |
---|
Presurgical
|  |  | 770 ± 19 |  |
4 weeks
| 0.626 ± 0.126 | 0.656 ± 0.0781 | 680 ± 52 |  |
8 weeks
| 0.922 ± 0.111 | 0.827 ± 0.105 | 610 ± 37* |  |
12 weeks
| 1.14 ± 0.0923* | 1.07 ± 0.0809* | 690 ± 57 | 18 ± 0.82 2.9 ± 0.58 |
- Values are mean ± standard error from the measured SBC diameter and superficial volumetric bone mineral density (vBMD) occurring over time. OA grade (OARSI), acquired from the histological analysis, is provided for the final time point only and presented versus the contralateral limb score underneath. *vBMD = P < 0.05 versus presurgical, *diameter = P < 0.05 versus 4 weeks. ACLX, anterior cruciate ligament transection with partial medial meniscectomy; CT, computed tomography; MRI, magnetic resonance imaging; OARSI, Osteoarthritis Research Society International.