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Table 1 Distribution of HLA-B*51 and HLA-B*52 allele groups in healthy controls and Takayasu's arteritis patientsa

From: Takayasu's arteritis is associated with HLA-B*52, but not with HLA-B*51, in Turkey

Characteristics n HLA-B*52+ (%) P OR (95% CI) HLA-B*51+ (%) P
HC 210 14 (6.7)    52 (24.8)  
   Men 97 6 (6.2)    23 (23.7)  
   Women 113 8 (7.1)    29 (25.7)  
TAK 330 69 (20.9) 0.000 3.7 (2.02 to 6.77) 75 (22.7) 0.64
   Men 42 7 (16.7) 0.063   12 (28.6) 0.53
   Women 288 62 (21.5) 0.000 3.6 (1.66 to 7.79) 63 (21.9) 0.43
Age at onset       
   < 40 years 240 58 (24.2) 0.024 0.43 (0.20 to 0.91) 49 (20.4) 0.11
   ≤ 40 years 75 9 (12.0)    22 (29.3)  
Angiographic subtypeb       
   Type I 130 17 (13.1) 0.005 0.43 (0.23 to 0.78) 28 (21.5) 0.78
   Type Iia 21 8 (38.1)    6 (28.6)  
   Type Iib 9 3 (33.3)    2 (22.2)  
   Type III 13 5 (38.5)    3 (23.1)  
   Type IV 15 3 (20.0)    1 (6.7)  
   Type V 142 34 (23.9)    35 (24.6)  
Surgery (all)       
   Present 66 9 (13.6) 0.092 0.51 (0.24 to 1.09) 13 (19.7) 0.62
   Not present 246 58 (23.6)    57 (23.2)  
Surgery after IS treatment       
   Present 36 7 (19.4) 1.0   9 (25) 0.67
   Not present 273 59 (21.6)    60 (22.0)  
Refractory disease       
   Refractory 114 31 (27.4) 0.084 1.68 (0.97 to 2.93) 20 (17.5) 0.12
   Not refractory 193 35 (18.1)    49 (25.4)  
  1. aHC, healthy control; IS, immunosuppressive; TAK, Takayasu's arteritis. Subgroup analysis was performed between groups with or without known clinical features. bP vs other all other subtypes.