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Table 3 Predictors of low power Doppler activity (≤ 1) at 12 months

From: Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugs

  Univariable analyses Multivariable analyses*
  OR (95%CI) P OR (95% CI) P
Overall population     
   CXCL13 third tertile 0.19 (0.07 to 0.54) 0.002 0.16 (0.04 to 0.58) 0.005
   CRP third tertile 0.58 (0.21 to 1.56) 0.28 - -
   ESR third tertile 0.61 (0.22 to 1.7) 0.35 - -
   ACPA (positive) 0.40 (0.14 to 1.15) 0.09 0.41 (0.12 to 1.40) 0.15
   baseline PD score (third tertile) 0.94 (0.31 to 2.83) 0.91 - -
DAS < 2.4     
   CXCL13 third tertile 0.05 (0.01 to 0.42) 0.006 0.06 (0.01 to 0.55) 0.01
   CRP third tertile 0.53 (0.12 to 2.37) 0.41 - -
   ESR third tertile 1.22 (0.22 to 6.72) 0.82 - -
   ACPA (positive) 0.46 (0.09 to 2.22) 0.33 - -
   baseline PD score (third tertile) 0.57 (0.11 to 2.86) 0.49 - -
  1. *Adjusted for age, gender, symptoms duration, glucocorticoid comedication, total amount of methotrexate administered and each of the variables with P < 0.2 in univariable analysis.
  2. ACPA, anti-citrullinated protein antibodies; CRP, C-reactive protein; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; PD, Power Doppler. CXCL13 third tertile: > 100 pg/ml. CRP third tertile: > 2.3 mg/dl. ESR third tertile: > 39 mm/1 h baseline PD score third tertile: > 7