| |
Univariable analyses
|
Multivariable analyses*
|
|---|
| |
OR (95%CI)
|
P
|
OR (95% CI)
|
P
|
|---|
|
Overall population
| | | | |
|
CXCL13 third tertile
|
0.19 (0.07 to 0.54)
|
0.002
|
0.16 (0.04 to 0.58)
|
0.005
|
|
CRP third tertile
|
0.58 (0.21 to 1.56)
|
0.28
|
-
|
-
|
|
ESR third tertile
|
0.61 (0.22 to 1.7)
|
0.35
|
-
|
-
|
|
ACPA (positive)
|
0.40 (0.14 to 1.15)
|
0.09
|
0.41 (0.12 to 1.40)
|
0.15
|
|
baseline PD score (third tertile)
|
0.94 (0.31 to 2.83)
|
0.91
|
-
|
-
|
|
DAS < 2.4
| | | | |
|
CXCL13 third tertile
|
0.05 (0.01 to 0.42)
|
0.006
|
0.06 (0.01 to 0.55)
|
0.01
|
|
CRP third tertile
|
0.53 (0.12 to 2.37)
|
0.41
|
-
|
-
|
|
ESR third tertile
|
1.22 (0.22 to 6.72)
|
0.82
|
-
|
-
|
|
ACPA (positive)
|
0.46 (0.09 to 2.22)
|
0.33
|
-
|
-
|
|
baseline PD score (third tertile)
|
0.57 (0.11 to 2.86)
|
0.49
|
-
|
-
|
- *Adjusted for age, gender, symptoms duration, glucocorticoid comedication, total amount of methotrexate administered and each of the variables with P < 0.2 in univariable analysis.
- ACPA, anti-citrullinated protein antibodies; CRP, C-reactive protein; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; PD, Power Doppler. CXCL13 third tertile: > 100 pg/ml. CRP third tertile: > 2.3 mg/dl. ESR third tertile: > 39 mm/1 h baseline PD score third tertile: > 7
