|
Cardiovascular risk factors
| | | |
|
Systemic arterial hypertension
|
14.3
|
24.1
|
1.11 (0.92 to 1.34)
|
|
Diabetes mellitus
|
4.4
|
6.9
|
1.08 (0.82 to 1.42)
|
|
Coronary heart disease
|
4.4
|
13.3
|
1.17 (0.98 to 1.39)
|
|
Hypercholesterolaemia
|
19.1
|
13.3
|
0.92 (0.70 to 1.21)
|
|
History of smoking
|
31.8
|
42.6
|
1.09 (0.92 to 1.29)
|
|
Cigarette smoking (pack-years)
|
15 (10 to 21)
|
20 (9 to 30)
|
P = 0.69
|
|
Medication
| | | |
|
Antidepressant, sedative, neuroleptic or antiepileptic
|
4.4
|
9.1
|
1.12 (0.89 to 1.40)
|
|
Thiazides or spironolactone
|
4.4
|
7.0
|
1.08 (0.82 to 1.43)
|
|
Alcohol consumption (> 2 units/day)
|
0
|
13.7
|
1.27 (1.15 to 1.40)*
|
|
Other
| | | |
|
Depression
|
4.6
|
9.0
|
1.11 (0.88 to 1.39)
|
|
Central nervous system problems
|
0
|
3.9
|
1.23 (1.13 to 1.35)*
|
|
Prostatic disease
|
0
|
8.4
|
1.24 (1.13 to 1.36)*
|
|
Hormonal (hypogonadism, hyperprolactinaemia)
|
0
|
2.8
|
1.23 (1.11 to 1.36)
|
|
Number of comorbidities per patient
| | | |
|
At least one comorbidity
|
52.2
|
61.5
|
1.07 (0.90 to 1.28)
|
|
At least two comorbidities
|
13.0
|
36.5
|
1.21 (1.05 to 1.40)*
|
|
At least three comorbidities
|
4.4
|
14.4
|
1.17 (1.00 to 1.34)*
|
|
At least four comorbidities
|
0
|
5.8
|
1.23 (1.13 to 1.35)*
|
|
At least five comorbidities
|
0
|
1
|
1.22 (1.13 to 1.33)*
|
