| |
Erectile dysfunction severity
| |
|---|
| |
Mild (n= 25)
|
Mild to moderate (n= 26)
|
Moderate (n= 14)
|
Severe (n= 40)
|
P value
|
|---|
|
IIEF-5 score
|
19 (18 to 20)
|
14 (13 to 16)
|
10 (8 to 11)
|
5 (5 to 6)
|
< 0.001*
|
|
Age (years)
|
50.5 (45.3 to 61.0)
|
54.1 (47.1 to 63.9)
|
54.9 (48.6 to 62.0)
|
57.3 (48.8 to 64.0)
|
< 0.001*
|
|
Duration of erectile dysfunction (years)
|
1.0 (0.6 to 2.3)
|
1.2 (0.1 to 2.6)
|
2.8 (0.1 to 5.0)
|
4.0 (1.0 to 6.4)
|
0.08
|
|
Diffuse SSc
|
59.1
|
47.6
|
72.7
|
82.1
|
0.08
|
|
C-reactive protein elevation
|
9.1
|
18.2
|
41.7
|
37.4
|
0.06
|
|
Forced vital capacity (% predicted)
|
99 (86 to 108)
|
100 (91 to 108)
|
84 (78 to 90)
|
81 (66 to 98)
|
0.006*
|
|
Forced vital capacity < 80%
|
16.7
|
6.3
|
33.3
|
47.6
|
0.01*
|
|
DLCO (% predicted)
|
70 (53 to 81)
|
79 (61 to 90)
|
64 (49 to 69)
|
56 (45 to 74.5)
|
0.02*
|
|
PAPsys (mmHg)
|
32 (25 to 38)
|
25 (21 to 29)
|
27 (19 to 36)
|
35 (25 to 39)
|
0.006*
|
|
PAPsys > 40 mmHg
|
25
|
10.0
|
16.7
|
38.5
|
0.02*
|
|
EULAR SSc activity score
|
1.5 (0.5 to 3.0)
|
2.5 (1.0 to 4.5)
|
3.5 (3.0 to 5.5)
|
2 (0.5 to 3.5)
|
0.047*
|
|
High SSc activity (score > 3)
|
26.7
|
47.1
|
83.3
|
40.0
|
0.02*
|
- Data presented as median (interquartile range) or percentage. DLCO, diffusion capacity of the lung for carbon monoxide; IIEF-5, International Index of Erectile Function-5; PAPsys, systolic pulmonary arterial pressure; SSc, systemic sclerosis. *Significant at P < 0.05.
