Table 4 Organ involvement by severity of erectile dysfunction
Erectile dysfunction severity | |||||
|---|---|---|---|---|---|
Mild (n= 25) | Mild to moderate (n= 26) | Moderate (n= 14) | Severe (n= 40) | P value | |
IIEF-5 score | 19 (18 to 20) | 14 (13 to 16) | 10 (8 to 11) | 5 (5 to 6) | < 0.001* |
Age (years) | 50.5 (45.3 to 61.0) | 54.1 (47.1 to 63.9) | 54.9 (48.6 to 62.0) | 57.3 (48.8 to 64.0) | < 0.001* |
Duration of erectile dysfunction (years) | 1.0 (0.6 to 2.3) | 1.2 (0.1 to 2.6) | 2.8 (0.1 to 5.0) | 4.0 (1.0 to 6.4) | 0.08 |
Diffuse SSc | 59.1 | 47.6 | 72.7 | 82.1 | 0.08 |
C-reactive protein elevation | 9.1 | 18.2 | 41.7 | 37.4 | 0.06 |
Forced vital capacity (% predicted) | 99 (86 to 108) | 100 (91 to 108) | 84 (78 to 90) | 81 (66 to 98) | 0.006* |
Forced vital capacity < 80% | 16.7 | 6.3 | 33.3 | 47.6 | 0.01* |
DLCO (% predicted) | 70 (53 to 81) | 79 (61 to 90) | 64 (49 to 69) | 56 (45 to 74.5) | 0.02* |
PAPsys (mmHg) | 32 (25 to 38) | 25 (21 to 29) | 27 (19 to 36) | 35 (25 to 39) | 0.006* |
PAPsys > 40 mmHg | 25 | 10.0 | 16.7 | 38.5 | 0.02* |
EULAR SSc activity score | 1.5 (0.5 to 3.0) | 2.5 (1.0 to 4.5) | 3.5 (3.0 to 5.5) | 2 (0.5 to 3.5) | 0.047* |
High SSc activity (score > 3) | 26.7 | 47.1 | 83.3 | 40.0 | 0.02* |