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Table 4 Organ involvement by severity of erectile dysfunction

From: Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group

  Erectile dysfunction severity  
  Mild (n= 25) Mild to moderate (n= 26) Moderate (n= 14) Severe (n= 40) P value
IIEF-5 score 19 (18 to 20) 14 (13 to 16) 10 (8 to 11) 5 (5 to 6) < 0.001*
Age (years) 50.5 (45.3 to 61.0) 54.1 (47.1 to 63.9) 54.9 (48.6 to 62.0) 57.3 (48.8 to 64.0) < 0.001*
Duration of erectile dysfunction (years) 1.0 (0.6 to 2.3) 1.2 (0.1 to 2.6) 2.8 (0.1 to 5.0) 4.0 (1.0 to 6.4) 0.08
Diffuse SSc 59.1 47.6 72.7 82.1 0.08
C-reactive protein elevation 9.1 18.2 41.7 37.4 0.06
Forced vital capacity (% predicted) 99 (86 to 108) 100 (91 to 108) 84 (78 to 90) 81 (66 to 98) 0.006*
Forced vital capacity < 80% 16.7 6.3 33.3 47.6 0.01*
DLCO (% predicted) 70 (53 to 81) 79 (61 to 90) 64 (49 to 69) 56 (45 to 74.5) 0.02*
PAPsys (mmHg) 32 (25 to 38) 25 (21 to 29) 27 (19 to 36) 35 (25 to 39) 0.006*
PAPsys > 40 mmHg 25 10.0 16.7 38.5 0.02*
EULAR SSc activity score 1.5 (0.5 to 3.0) 2.5 (1.0 to 4.5) 3.5 (3.0 to 5.5) 2 (0.5 to 3.5) 0.047*
High SSc activity (score > 3) 26.7 47.1 83.3 40.0 0.02*
  1. Data presented as median (interquartile range) or percentage. DLCO, diffusion capacity of the lung for carbon monoxide; IIEF-5, International Index of Erectile Function-5; PAPsys, systolic pulmonary arterial pressure; SSc, systemic sclerosis. *Significant at P < 0.05.