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Table 4 Relative risk of developing RF-positive and RF-negative rheumatoid arthritis for subjects reporting exposure to cosmetics

From: Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study

  RF+RA RF-RA
Exposure Number of exposed
cases/controlsa
RRb 95% CI RRc 95% CI Number of exposed
cases/controlsa
RRb 95% CI RRc 95% C
  Women Women
A 73/118 1.0 Reference 1.0 Reference 30/118 1.0 Reference 1.0 Reference
B 118/174 1.1 0.7-1.5 1.0 0.6-1.5 60/174 1.3 0.8-2.2 1.2 0.7-2.1
C 115/230 0.8 0.5-1.2 0.7 0.5-1.1 63/230 1.1 0.6-1.7 0.9 0.5-1.7
D 215/370 0.9 0.6-1.3 0.8 0.6-1.2 104/370 1.1 0.7-1.7 1.0 0.6-1.7
E 139/294 0.7 0.5-1.0 0.7 0.4-1.0 94/294 1.2 0.7-2.0 1.0 0.6-1.8
  Men Men
A 212/359 1.0 Reference 1.0 Reference 103/359 1.0 Reference 1.0 Reference
B 31/78 0.6 0.4-1.0 0.7 0.4-1.1 22/78 1.0 0.6-1.6 1.0 0.6-1.8
C 14/27 0.8 0.4-1.6 0.8 0.4-1.6 8/27 0.9 0.4-2.1 1.0 0.4-2.3
D 7/13 1.0 0.4-2.5 1.0 0.4-2.7 5/13 1.3 0.5-4.0 1.3 0.4-4.1
E 3/6 0.8 0.2-3.3 0.5 0.1-2.8 1/6 1.0 0.1-9.0 0.9 0.1-9.1
  All All
A 285/477 1.0 Reference 1.0 Reference 133/477 1.0 Reference 1.0 Reference
B 149/252 0.9 0.6-1.2 0.8 0.6-1.1 82/252 1.1 0.8-1.6 1.1 0.7-1.6
C 129/257 0.8 0.6-1.1 0.7 0.5-1.1 71/257 1.0 0.7-1.6 0.9 0.6-1.5
D 222/383 0.9 0.6-1.2 0.8 0.6-1.2 109/383 1.1 0.7-1.7 1.1 0.7-1.7
E 142/300 0.7 0.5-1.0 0.7 0.5-1.0 95/300 1.2 0.7-1.9 1.0 0.6-1.7
  1. Relative risk (RR) together with 95% confidence interval (CI) of developing rheumatoid factor (RF)-positive rheumatoid arthritis (RA), and RF-negative RA for subjects 18 to 70 years old reporting different amounts of exposure to cosmetics compared with those low exposed (A), by gender. aInformation on RF status is missing for one female case in comparison with Table 3. bAdjusted for age, living area and gender where appropriate. cAdjusted for age, living area, gender, socio-economic status and smoking where appropriate.