From: Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study
 | RA (n= 17) | Control (n= 14) | Myocarditis (n= 5) | Scleroderma (n= 10) | P a |
---|---|---|---|---|---|
Demographics and reported autopsy features | Â | Â | Â | Â | Â |
Age, years | 68 ± 12 | 67 ± 12 | 61 ± 13 | 54 ± 13 | 0.85 |
Female, n (%) | 15 (88) | 11 (79) | 2 (40) | 7 (70) | 0.64 |
Caucasian, n (%) | 12 (71) | 12 (86) | 4 (80) | 5 (50) | 0.41 |
PMI, median (%) | 19 (13-23) | 20 (9-28) | 25 (21-27) | 24 (19-39) | 0.92 |
Coronary atherosclerosis, any reported; n (%) | 7 (41) | 7 (50) | 2 (40) | 4 (40) | 0.62 |
Mild or moderate, n (%) | 4 (24) | 6 (43) | 1 (20) | 3 (30) | 0.44 |
Severe, n (%) | 3 (18) | 1 (7) | 1 (20) | 1 (10) | 0.60 |
Histologic findings | Â | Â | Â | Â | Â |
Myocarditis, n (%) | 0 (0) | 1 (6) | 5 (100) | 0 (0) | 1.00 |
Interstitial fibrosis, n (%) | 14 (81) | 12 (86) | 3 (60) | 7 (70) | 1.00 |
Replacement fibrosis, n (%) | 3 (19) | 4 (29) | 1 (20) | 3 (30) | 0.68 |
Cardiomyocyte hypertrophy, n (%) | 11 (63) | 9 (64) | 2 (40) | 7 (70) | 1.00 |