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Table 2 Comparison of FMD and NTG values in RA patients according to rs599839 polymorphism

From: The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis

 

FMD%

mean ± SD (n)

P

NTG%

mean ± SD (n)

P

rs599839

    

Allele

    

A

6.01 ± 5.15 (210)

0.08

16.95 ± 8.14 (210)

0.06

G

4.61 ± 3.94 (46)

 

14.52 ± 6.92 (46)

 

Genotype

    

AA

6.15 ± 5.42 (87)

0.16

17.34 ± 8.34 (87)

0.19

AG

5.35 ± 3.70 (36)

 

15.04 ± 7.01 (36)

 

GG

1.94 ± 3.98 (5)

 

12.66 ± 6.99 (5)

 

AG+GG

4.93 ± 3.85 (41)

0.20

14.74 ± 6.96 (41)

0.09

  1. FMD, flow-mediated endothelium-dependent (post-ischemia) vasodilatation; NTG, flow-mediated endothelial independent (post-nitroglycerin) vasodilatation; RA, rheumatoid arthritis; SD, standard deviation
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Arthritis Research & Therapy

ISSN: 1478-6362

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