Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity

Table 3 Expression of CX3CL1 and CX3CR1 in the muscle tissue from each of the patients

	Polymyositis		Dermatomyositis
	Pt1	Pt2	Pt1	Pt2	Pt3
CX3CL1
Infiltrated mononuclear cells	++	+++	+++	++++	+++
Endothelial cells	++	++	+++	+++	+++
CX3CR1
CD4⁺ T cells	+	+	+	+	+
CD8⁺ T cells	++++	+++	++++	+++	++++
CD68⁺ macrophages	+++++	+++++	+++++	+++++	+++++

Muscle tissue sections were scored: -, no staining; +, few of the cells positively stained; ++, some (less than one-half) of the cells stained; +++, approximately one-half of the cells stained; ++++, more than one-half of the cells stained; +++++, most cells stained.

ISSN: 1478-6362