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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage

Figure 3

Bovine articular chondrocytes in micromass culture. Bovine articular chondrocytes grown in micromass cultures were left untreated (A) and (C) or treated with transforming growth factor β (TGF-β) (B) and (D) for 7 days. Cultures were stained for Alcian blue (A) and (B) or alkaline phosphatase (C) and (D). Quantification of staining showed an increase in Alcian blue staining (E) and a decrease in alkaline phosphatase activity after treatment with TGF-β (F). *P-value < 0.05 by t-test. pNP: p-nitophenol.

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