| Baseline | 6 months | 12 months | 18 months | 24 months |
---|---|---|---|---|---|
Total IgG (g/L) | 13.4 (5.4 to 16.5) | 10.5 (5.4 to 15.0)b | 10.4 (5.2 to 13.6) | 9.35 (5.2 to 13.6) | 9.15 (5.1 to 12.2)c |
   ACPA-IgG (U/ml) | 423 (65.6 to 1116) | 349 (47.0 to 647)b | 243 (43.9 to 410) | 215 (57.2 to 361) | 199 (43.6 to 354)c |
   Measles-IgG (U/ml) | 3.72 (2.43 to 4.71) | 3.81 (2.75 to 5.03) | 3.84 (2.53 to 5.03) | 3.58 (2.63 to 5.04) | 3.67 (2.81 to 4.94) |
   Mumps-IgG (U/ml) | 3.16 (0.65 to 4.67) | 3.31 (0.53 to 4.77) | 3.31 (0.46 to 4.89) | 3.33 (0.64 to 4.78) | 3.62 (0.67 to 5.11) |
   Rubella-IgG (U/ml) | 101 (50.2 to 303) | 100 (29.7 to 310) | 91.6 (20.5 to 333) | 103 (25.6 to 311) | 106 (26.9 to 301) |
Total IgM (g/L) | 1.7 (0.6 to 3.7) | 1.2 (0.3 to 2.1)b | 1.1 (0.2 to 2.2) | 1.0 (0.2 to 1.9) | 0.9 (0.2 to 2.0)c |
   ACPA-IgM (U/ml) | 35.3 (23.4 to 101) | 24.4 (16.3 to 72.9)b | 21.4 (16.2 to 49.1) | 19.8 (14.4 to 37.0) | 20.0 (11.8 to 30.8)c |
   RF-IgM (U/ml) | 76.0 (10.0 to 792) | 32 (8.0 to 385)b | 16 (5 to 555) | 13 (2.0 to 310) | 10 (1 to 208)c |
Total IgA (g/L) | 2.0 (1.2 to 5.5) | 1.7 (1.0 to 5.7)b | 1.8 (0.8 to 5.5) | 1.6 (0.8 to 4.3) | 1.55 (0.8 to 4.2)c |
   ACPA-IgA (U/ml) | 20.7 (3.16 to 90.8) | 12.5 (5.22 to 87.4) | 9.79 (2.81 to 97.9) | 8.49 (3.69 to 60.3) | 8.50 (2.63 to 44.4)c |