Figure 2From: The Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to manPathways of nitric oxide (NO) formation and effects on articular chondrocytes. COX = cyclooxygenase, IL-1Ra = interleukin-1 receptor antagonist, iNOS = inducible nitric oxide synthase, NF = nuclear factor, PGs = prostaglandins, - refers to inhibition; + to stimulation. Reproduced from figure 110.3 with permission from [80].Back to article page