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Table 1 IL-22 production by activated synovial fluid (SF) and peripheral blood (PB) CD3+ T cells.

From: Functional role of IL-22 in psoriatic arthritis

   IL-22 concentration (pg/ml)
   24 hr. Incubation 48 hr. Incubation
   Unstimulated (Mean ± SEM) CD3/CD28 Stimulated (Mean ± SEM) PMA/Ionomycin Stimulated (Mean ± SEM) Unstimulated (Mean ± SEM) PHA Stimulated (Mean ± SEM)
PsA ( n = 10) SF-T cells 3.85 ± 0.51 14.57 ± 0.80*$ 18.92 ± 0.89**#$ 4.21 ± 0.5 95.55 ± 7.81***#$
  PB-T cells 3.65 ± 0.23 10.44 ± 0.66* 12.83 ± 0.79* 4.28 ± 0.44 48.13 ± 6.38***$
RA ( n = 10) SF-T cells 4.22 ± 0.31 14.32 ± 0.96*$ 18.91 ± 1.97**#$ 4.63 ± 0.37 81.63 ± 5.90***#$
  PB-T cells 4 ± 0.16 10.56 ± 0.48* 11.88 ± 0.18* 4.1 ± 0.26 53.08 ± 4.58***$
OA ( n = 8) SF-T cells 4.63 ± 0.57 8.61 ± 0.79 13.59 ± 0.81* 4.79 ± 0.12 39.06 ± 3.92***
  PB-T cells 3.94 ± 0.22 6.88 ± 0.34 11.44 ± 0.78* 4.04 ± 0.18 32.78 ± 2.56***
  1. * p < 0.05, **p < 0.01, compared to 24 hr unstimulated media; ***p < 0.001, compared to 48 hr unstimulated media, Wilcoxon matched pairs signed rank test. #p < 0.05, compared to PB-T cells; $p < 0.05, $$p < 0.01, compared to that of OA, Mann Whitney test.