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Table 4 Cytokine levels in SLE patients according to steroids intake during the first and third trimester.

From: Effect of pregnancy on serum cytokines in SLE patients

  1st trimester   3rd trimester  
  High dose PDN Low dose PDN P High dose PDN Low dose PDN P
TNF-α 21.70 (5.75 to 64.75) 10.70 (6.50 to 38.32) n.s. 18.50 (5.25 to 34.75) 10.25 (5.05 to 25.45) n.s.
INF-γ 4.80 (1.15 to 15.30) 3.75 (1.32 to 11.62) n.s. 8.20 (0.40 to 14.05) 3.40 (1.12 to 10.00) n.s.
IL-1α 0.50 (0.15 to 5.70) 1.90 (0.50 to 7.90) n.s. 1.20 (0.0 to 2.85) 1.30 (0.25 to 5.95) n.s.
IL-1β 0.80 (0.25 to 2.05) 1.30 (0.45 to 4.20) n.s. 0.10 (0.0 to 5.80) 0.90 (0.15 to 2.40) n.s.
IL-2 6.00 (3.10 to 14.00) 3.55 (1.50 to 13.92) n.s. 4.80 (1.90 to 13.45) 4.40 (1.50 to 11.90) n.s.
IL-8 8.70 (2.55 to 25.65) 8.65 (4.62 to 33.70) n.s. 3.90 (0.50 to 6.40) 4.70 (2.10 to 19.80) n.s.
IL-12 6.40 (3.85 to 20.05) 8.35 (1.87 to 31.60) n.s. 3.20 (0.50 to 21.30) 4.45 (2.12 to 24.97) n.s.
IL-10 2.10 (1.20 to 8.45) 3.60 (1.22 to 13.57) n.s. 2.00 (1.35 to 9.50) 3.90 (1.37 to 9.67) n.s.
IL-6 6.50 (4.45 to 17.75) 8.20 (3.87 to 34.55) n.s. 6.30 (4.05 to 29.90) 7.70 (3.90 to 25.50) n.s.
  1. SLE patients who have taken high steroids dose: n = 27; SLE patients who have taken low steroids dose: 9. The median values (25th to 75th percentile) are expressed in pg/ml.