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Table 4 Cytokine levels in SLE patients according to steroids intake during the first and third trimester.

From: Effect of pregnancy on serum cytokines in SLE patients

 

1st trimester

 

3rd trimester

 
 

High dose PDN

Low dose PDN

P

High dose PDN

Low dose PDN

P

TNF-α

21.70 (5.75 to 64.75)

10.70 (6.50 to 38.32)

n.s.

18.50 (5.25 to 34.75)

10.25 (5.05 to 25.45)

n.s.

INF-γ

4.80 (1.15 to 15.30)

3.75 (1.32 to 11.62)

n.s.

8.20 (0.40 to 14.05)

3.40 (1.12 to 10.00)

n.s.

IL-1α

0.50 (0.15 to 5.70)

1.90 (0.50 to 7.90)

n.s.

1.20 (0.0 to 2.85)

1.30 (0.25 to 5.95)

n.s.

IL-1β

0.80 (0.25 to 2.05)

1.30 (0.45 to 4.20)

n.s.

0.10 (0.0 to 5.80)

0.90 (0.15 to 2.40)

n.s.

IL-2

6.00 (3.10 to 14.00)

3.55 (1.50 to 13.92)

n.s.

4.80 (1.90 to 13.45)

4.40 (1.50 to 11.90)

n.s.

IL-8

8.70 (2.55 to 25.65)

8.65 (4.62 to 33.70)

n.s.

3.90 (0.50 to 6.40)

4.70 (2.10 to 19.80)

n.s.

IL-12

6.40 (3.85 to 20.05)

8.35 (1.87 to 31.60)

n.s.

3.20 (0.50 to 21.30)

4.45 (2.12 to 24.97)

n.s.

IL-10

2.10 (1.20 to 8.45)

3.60 (1.22 to 13.57)

n.s.

2.00 (1.35 to 9.50)

3.90 (1.37 to 9.67)

n.s.

IL-6

6.50 (4.45 to 17.75)

8.20 (3.87 to 34.55)

n.s.

6.30 (4.05 to 29.90)

7.70 (3.90 to 25.50)

n.s.

  1. SLE patients who have taken high steroids dose: n = 27; SLE patients who have taken low steroids dose: 9. The median values (25th to 75th percentile) are expressed in pg/ml.