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Table 1 Summary of studies assessing the relationship between inflammation on baseline STIR MRI of the spine and development of new syndesmophytes after 2 years of follow up

From: MRI and X-ray in axial spondyloarthritis: the relationship between inflammatory and structural changes

  Number of patients with new syndesmophytes at 2 years   
Study Yes No OR (95% CI) P-value
Baraliakos et al. [19]     
   Baseline VE+ (n = 163; 17.2%) 10 (6.5%) 153 (93.5%) 3.1 (1.4-7.1) 0.007
   Baseline VE- (n = 785; 82.8%) 16 (2.1%) 769 (97.9%)   
Maksymowych et al. [20]     
Anti-TNFα trial patients     
   Baseline CIL+ (n = 30) 6 (20%) 24 (80%) 4.6 (1.7-12.6) 0.007
   Baseline CIL- (n = 370) 19 (5.1%) 351 (94.9%)   
   Observational cohort patients     
   Baseline CIL+ (n = 28) 6 (15.8%) 32(84.2%) 6.3 (2.4-16.7) 0.001
   Baseline CIL- (n = 617) 23 (2.9%) 778 (97.1%)   
Van der Heijde et al. [21]     
   Baseline DVU+ (n = 297) 36 (12.1%) 261 (87.9%) 1.9 (1.3-2.8) 0.002
   Baseline DVU- (n = 1,707) 115 (6.7%) 1,592 (93.3%)   
  1. CIL, vertebral corner inflammatory lesion [20]; DVU, discovertebral unit [21]; OR, odds ratio; STIR, short tau inversion recovery; VE, vertebral edge [19].