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Table 2 Comparison of PET-CT outcome with MRI and conventional radiography of subpopulation scanned with [18F]FDG, [11C](R)PK11195, and [18F]fluoride

From: Bone formation rather than inflammation reflects Ankylosing Spondylitis activity on PET-CT: a pilot study

Patient Anatomic location X-ray PET-CT a MRI
    Score b Level Lesion [18F]FDG [18F]Fluoride T1+Gd STIR
   Cervical 0 2 p FA -    - -
      3 p FA         
            7 p 7 p 7 p
      8 a SC 8a 8 a 8 a 8 a
      9 a SC    9 a 9 a 9 a
1 Spine Thoracic 0 10 a SC    10 a 10 a 10 a
      11 a SC    11 a 11 a 11 a
      12 a SC         
   Lumbar 0 4 p FA - 4 p - -
      5 p FA    5 p     
  Sacroiliac joints 2 2 R L SC SC         
   Cervical 0 - - - - 6 a 6 a
              7 a 7 a
            1 p 1 p 1 p
            6 p     
            8 p     
   Thoracic 0 9 a/p SQ    9 p     
  Spine     10 a/p SQ 10a 10 p     
2      11 a/p SQ 11a 11 p     
      12 a/p SQ         
          -    2 a 2 a
            3 a     
   Lumbar 2 4 a SQ         
            5 a     
  Sacroiliac joints 4 3 R L Ank SC - - R L Ank
sfmi
Ank
sfmi
Ank
sfmi
Ank
sfmi
  1. Levels on positron emission tomography-computed tomography (PET-CT) and magnetic resonance imaging (MRI) scans are hotspots with increased signal. a[11C](R)PK11195 is not presented, because all scans were negative. bX-ray according to modified Stoke Ankylosing Spondylitis Spinal Score (m-SASSS) (0 to 72). a, anterior; Ank, ankylosis; [11C](R)PK11195, PK11195 [(R)-1-(2-chlorophenyl)-N-methyl-N(1-methyl-propyl)-3-soquinoline carboxamide]; FA, facet arthrosis; L, left; p, posterior; R, right; SC, sclerosis; sfmi, subchondral fatty marrow infiltration; SQ, squaring; STIR, short-tau inversion recovery; T1+Gd, gadolinium contrast uptake on T1 images.