Weight and weight distribution. During the course of the experiment, weight increased in all treatment groups (left); however, rats with medial meniscus transection (MMT) surgery (open diamond) added less weight over time than naïve control animals (solid diamond) and rats with medial collateral ligament (MCL) sham surgery (shaded diamond, P = 0.003, P = 0.011, respectively). Imbalanced weight distributions were not observed in any group at any time (right: naïve control, closed circle; MCL sham, shaded circle; MMT surgery, open circle). Data are presented as mean ± SEM. *Differences between surgical groups at a level of P < 0.05.